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MIT student blogger Hamsika C. '13

Cancer by Hamsika C. '13


Of all the student groups I am involved with at MIT, the one that brings me the most happiness is Camp Kesem MIT. Those of you who have stuck with me throughout my blogging career have heard about CK before. Those of you who haven’t – well, I’m about to tell you about it :)

Camp Kesem MIT is a one-week, free summer camp that takes place towards the end of August and is geared towards kids whose parents have been affected by cancer. Each summer, a combination of kids and counselors (all of whom are MIT students) come together for a week of pure camp fun – filled with sports, nature activities, arts and crafts, ropes courses, drama rotations, swimming, hiking, and more. Planning for each camp session is done entirely by a coordinator board made up of ~15 MIT students; this board starts preparing for the following Camp session as soon as the present session is done.

I was a counselor for Camp Kesem MIT during my freshman and sophomore summers at MIT, and I’ve been a part of the coordinator board for a year and a half now. I LOVE CAMP. Throughout the year, we hold a number of events and fundraisers on campus to raise the $65,000 we need to make Camp Kesem happen each summer.

One such event took place this past weekend: The Camp Kesem-SAE Date Auction. SAE (Sigma Alpha Epsilon) is one of MIT’s fraternities and has been our partner for the Date Auction event for three years now. During the event, a number of MIT students are “auctioned” off, with gift cards to local restaurants and businesses. Typically, a “date” is bought by his or her friends, who pool together and “buy” their friend for an impressive sum. (I hope I’m doing a decent and not-sketchy job of describing this; please feel free to question me about any details that seem awkward – it’s an awesome event, I promise!) The businesses that donated prizes to this year’s date auction were California Pizza Kitchen, F1 Racing, Vapiano’s, Melting Pot, among other places. We raised over $6600 in just two hours through this Date Auction event!!

CK Counselors at SAE-CK Date Auction 2012


Every time I do something CK-related, I’m reminded of how lucky I am to have a happy, healthy family that hasn’t been affected by cancer. The kids I meet at Camp are so strong and resilient – each year I go to Camp, I’m blown away by their maturity and their stories. They’re the best kids ever <3

To add a personal touch to this blog entry, I want to introduce Jenn Lai ‘11– an MIT alum and a Rhodes Scholar. This is her story with cancer–


I’ve always been fascinated by personal stories. Everyone has pivotal experiences, those experiences that become skyscrapers in their life landscape, forever altering their perception of things around them. It’s just so happened that my skyscrapers were built by something called cancer.
When I was seven years old, my mother passed away from cancer. At the time, I had no idea what cancer was; I hardly even understood what was going on around me. All I knew was that there was a thing called cancer and that it was bad.

It wasn’t until some of my high school biology classes that I started to learn about the biological underpinnings of cancer. The topic fascinated me; it was sort of a guilty pleasure to learn about cancer. It gave me a glimpse into what occurred in my mother’s body, bringing me one step closer to understanding what had happened so many years ago. Cancer, I learned, is generally a disease of the old. As our bodies age, cells accumulate mutations in their growth mechanisms driving them to eventually overtake the body. I could imagine these malignant cells growing without bound in my mother’s body. Yet something didn’t make sense. My mom wasn’t old. She was forty.

There comes a time when we start to realize that some traits are hereditary: height, eye color, hair color, premature death by cancer. I didn’t know exactly what kind of cancer my mother had– I had never asked– but I had a hunch that whatever it was, I was likely to have it too. I delved into studying cancer, perhaps because I was simply hooked, perhaps because I was trying to understand my mother’s death, perhaps because I was trying to save myself.

It was around the time that I was applying to MD/PhD programs at the end of my MIT career that I started to do a little more digging. In trying to distill my reasons for wanting to become a physician scientist, it only made sense to investigate my own medical history. My mother had both breast and stomach cancer, I found out. She was diagnosed with ductal breast cancer in January 1997. The prognosis after surgery and radiation was good. Several months later, after undergoing surgical exploration for a case of ascites, build up of fluid in the peritoneal cavity, the surgeons found invasive gastric cancer. She passed away in September 1997. My maternal grandfather also passed away from some form of gastric cancer, as did a maternal aunt.

Curious, I typed into my Google search bar: hereditary gastric cancer. Among the first results that came up were some articles about hereditary diffuse gastric cancer (HDGC). I clicked on one, then another, then another. HDGC, I found out, is a relatively rare form of hereditary gastric cancer that is passed in an autosomal dominant fashion–if one parent is affected, each offspring has a fifty percent chance of also being affected. About fifty percent of HDGC cases can be linked to a gene mutation in CDH1, which encodes for the cell adhesion protein E-cadherin. Mutation carriers have about an 80%/70% (female/male) lifetime risk of developing the cancer by the age of 80, with median age of onset at around age 40. Diffuse gastric cancer is unfortunately very difficult to detect early by endoscopy, as the cancer grows in clusters in the lining of the stomach rather than in a distinct mass. By the time diffuse gastric cancer becomes symptomatic, it is often advanced and too late for treatment. Given the high likelihood of developing diffuse gastric cancer, it is now recommended that CDH1 mutation carriers undergo preventative removal of the entire stomach, a drastic but necessary measure.

After reading as much as I could about HDGC and CDH1, I looked into the criteria for getting a genetic test done and knew that I had to get tested. I had my blood drawn and sent to City of Hope in August 2010, and by December 2010 I knew that I am a CDH1 mutation carrier.
The implications of a positive test result are vast: coming to terms with destiny, deciding to get surgery and when, figuring out how it will affect my life and the plans I’d set out for myself. It came at a time when I knew I’d be moving to Oxford, then later dedicating at least eight years of my life to MD/PhD training with more years of medical training after. It’s been a long journey, which I could probably write an entire series of books on, and it’s not over yet. The main storyline is this: I have now decided to take time off from school to concentrate on my health. I will be having my surgery done in a couple of weeks at home in Honolulu, Hawaii, then will return to school in the fall.

The immediate response I get from most people is usually something along the lines of, “What!? You can live without a stomach?!” The short answer is yes– the stomach is actually surprisingly overrated. It’ll be an adjustment, and it’ll take time, but the fact is that it is both possible and necessary.
I’ve had plenty of time to think about if I am really making the right decision. Removing an organ is a big step. It is true that I wish I didn’t have to do it, but the reality is hard to ignore. After my mother passed away, I had a subconscious expectation that I wouldn’t live much beyond forty– maybe that’s why I have always worked so hard. Now I know that without this surgery, my life expectancy would be forty. As tumultuous as this entire experience has been, it is liberating to know that I will now have a pretty normal life expectancy. There is so much to do with that time– it really is a gift.
If I didn’t have a good reason to go into medicine and research before, I do now. The fact that preventative surgery is the only safe option for me sometimes makes me frustrated. It has also shown me that there are very real medical problems that still need to be solved, and this is only one of them. I can’t wait until I can move on to the next chapter of my life and start addressing these problems academically. In the meantime, I am focusing on enjoying every bite of every meal and the sunny Hawaiian days.


Jenn is the author of the blog gastronomically speaking, and she welcomes you to follow the rest of her journey. To find out more about gastric cancer and spread gastric cancer awareness, please visit No Stomach for Cancer

8 responses to “Cancer”

  1. Linh V. '13 says:

    You are amazing! smile I hope Camp Kesem will gain more and more support every year!

  2. Jenny '13 says:

    Thanks so much for sharing Hamsika! smile

  3. Joe says:

    Camp Kesem is a wonderful thing you are involved with Hamsika. It is amazing how resilient children are, even in the face of losing a parent. Keep up the great work!

  4. steph says:

    Jenn, you are so inspirational. This was a beautiful entry.

  5. Kshitij says:

    If I am admitted to MIT, Hamsika I would simply love to be a part of CK.What are the other activities at MIT for cancer afflicted kids and their families? Jenn, that was simply great and you are a living example of courage and fortitude!

  6. Marilyn Decker says:

    The more I read about MIT the more I realize how special it is and proud that I have a son who aspires to go there someday.

  7. Jon says:

    Love your blog. Amazing, touching story.

  8. Sambheet Krishna says:

    Human Cancer
    Cancer at the microscopic and marcroscopic level

    I am from India and have been studying about cancer for the past 1.5 years in my MBBS course from Manipal college of Medical Sciences, Nepal, I have found something interesting. Before discussing that let me recall how do cancerous cells behave? Cancerous cells aren’t regulated by the normal mechanisms for regulation of growth, they grow rapidly, to do so they lead to the angioneogenesis (formation of new blood vessels) so they can derrive nutrients and oxygen for their rapid growth, they outnumber other cells in their growth, they gain access to the nutrients meant for other normal nearby cells and make other cells starve and die, they invade different body tissues and make alterations in the mechanisms of the body as a whole, they become self sufficient in nutritional requirements, growth signals etc.

    Thats some of the features of the cancerous cells. But what I think is that what the cancerous cells are doing is same as whats happening at a larger scale. Think of Humans, how are we any different than cancerous cells?

    The growth of our population isn’t limited, its rapid, we are creating new supplies of food resources, water, electricity for us by extracting whatever is available in the earth and thats essential for our such growth, we are outnumbering the populations of all other animal species, we are making other species starve for food and resources and they are getting extinct. We have colonised all the places on earth and we are making alterations to the ecosystem of the earth as a whole, and we have become self sufficient in food, energy and what not?

    Can there be a mimicry of what we do at macroscopic (our) level inside our bodies itself? What if we consider the Earth to be a living body and the Humans to be cancerous cells? The same way there were normal inhabitants on the earth thousands of years ago, we altered them, we gained knowlege, led to self sufficiency in resources and flourished, we starved the other organisms for the same resources. This is exactly what the cancerous cells are doing in our body: they get mutated in their DNA (acquire knowledge) and gain control over resources for their unlimited growth.

    So coming to the big question, how do we control cancer? There is no cure when it is in later stages, we use chemotherapies, radiotherapy and surgery to remove the cancerous cells and affected area. But ultimately the person dies.

    So, according to my thinking, If indeed the cells in our body mimic what we are doing at macroscopic level, then if we stop doing all harm to the earth and the other species, we control the consumption of the resources on our planet, if we let other species live happily and share resources with them, if we check our poplation growth and maintain it at the level earth and other species can sustain; then only our body’s cells will mimic it and there will be no cancerous cells in our body.

    So, according to me that the cure of cancer; and that is to cure it at a macroscopic (our) level.
    I don’t know what other people will think about it; but to me it appears correct.

    What do you think?